{"jobs":[{"id":"cb2c1ef1-1b2d-4fb5-8c2b-854ecaa8766c","title":"Opportunistic","department":"Outliers & Polymaths","team":"Outliers & Polymaths","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2024-09-05T02:36:39.232+00:00","isListed":true,"isRemote":false,"workplaceType":"OnSite","address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/cb2c1ef1-1b2d-4fb5-8c2b-854ecaa8766c","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/cb2c1ef1-1b2d-4fb5-8c2b-854ecaa8766c/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About you

If you bring something exceptional to the table that could advance our mission to accelerate the design of AI to unlock biology and create better medicines, we want to hear from you. We value diverse perspectives and are ready to find greatness in unexpected places.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\nABOUT YOU\n\nIf you bring something exceptional to the table that could advance our mission to accelerate the design of AI to unlock biology and create better medicines, we want to hear from you. We value diverse perspectives and are ready to find greatness in unexpected places.\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"d8a52358-9942-4914-a90d-b62aa75cf456","title":"Business Operations","department":"Strategy","team":"Strategy","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2026-10-27T18:54:35.291+00:00","isListed":true,"isRemote":null,"workplaceType":null,"address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/d8a52358-9942-4914-a90d-b62aa75cf456","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/d8a52358-9942-4914-a90d-b62aa75cf456/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

We are hiring our first Business Operations lead. Someone who can take hard problems at Chai and own them end to end. You’ll be a high-trust partner and problem solver to our founders and functional leaders, working wherever you’re most needed.

The work ranges from renegotiating major contracts and making sure our compute spend matches what we actually need, to standing up new functions, to taking ownership of an office move or helping out with recruiting. We need someone who’s happy doing all of it, from the unglamorous to the mission-critical, and who leaves better systems behind each time. Someone with a nose for friction and pain points that no one else notices, and who handles them without delay.

Over time, we expect to build an operations team with people embedded across key functions, so that running exceptionally well stays one of Chai’s real advantages. You’ll be at the center of that from day one, and for those who want it, the path leads to running a function.

About you

You are a generalist with commercial instinct and a bias for action. You’re sophisticated enough to build the model behind a major contract and negotiate it yourself, and hands-on enough to chase down quotes for an office move or organize a dinner for a visiting executive. You pick up the phone rather than waiting for a perfect plan, and you use AI to move faster without trusting it blindly.

You have operated, not just advised. You are comfortable in any room and on any call. You gain credibility quickly in unfamiliar territory.

You may have been in the founder’s office or an early business operations hire at a high-growth startup, owned cost and supplier decisions at a company known for operational rigor, worked as a deployment strategist, or started a company of your own. If you trained in consulting or banking, you’ve since spent real time owning outcomes inside a company. A technical or scientific background is a plus; biotech experience isn’t required.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\nABOUT THE ROLE\n\nWe are hiring our first Business Operations lead. Someone who can take hard problems at Chai and own them end to end. You’ll be a high-trust partner and problem solver to our founders and functional leaders, working wherever you’re most needed.\n\nThe work ranges from renegotiating major contracts and making sure our compute spend matches what we actually need, to standing up new functions, to taking ownership of an office move or helping out with recruiting. We need someone who’s happy doing all of it, from the unglamorous to the mission-critical, and who leaves better systems behind each time. Someone with a nose for friction and pain points that no one else notices, and who handles them without delay.\n\nOver time, we expect to build an operations team with people embedded across key functions, so that running exceptionally well stays one of Chai’s real advantages. You’ll be at the center of that from day one, and for those who want it, the path leads to running a function.\n\n\nABOUT YOU\n\nYou are a generalist with commercial instinct and a bias for action. You’re sophisticated enough to build the model behind a major contract and negotiate it yourself, and hands-on enough to chase down quotes for an office move or organize a dinner for a visiting executive. You pick up the phone rather than waiting for a perfect plan, and you use AI to move faster without trusting it blindly.\n\nYou have operated, not just advised. You are comfortable in any room and on any call. You gain credibility quickly in unfamiliar territory.\n\nYou may have been in the founder’s office or an early business operations hire at a high-growth startup, owned cost and supplier decisions at a company known for operational rigor, worked as a deployment strategist, or started a company of your own. If you trained in consulting or banking, you’ve since spent real time owning outcomes inside a company. A technical or scientific background is a plus; biotech experience isn’t required.\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"2de4c9cf-bb01-4997-b0c9-534e4fd2db7b","title":"Antibody Engineering","department":"Science","team":"Science","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2026-02-15T20:51:41.556+00:00","isListed":true,"isRemote":false,"workplaceType":"OnSite","address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/2de4c9cf-bb01-4997-b0c9-534e4fd2db7b","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/2de4c9cf-bb01-4997-b0c9-534e4fd2db7b/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

We are looking for exceptional antibody engineers and computational protein designers to help us evaluate, expand and apply the capabilities of our de novo antibody design models. You'll join an elite team of biologists, computational scientists and AI researchers.

Scientists at Chai are power users and test pilots of our AI platform. We probe the design space for novel targets and formats, validate in silico solutions for function in the lab, and distill empirical rules from the results. We execute experimental programs at scale that guide, train and evaluate next generation models, working closely with our AI research team. We partner with scientists from the world's leading pharma companies to push their discovery programs into new territory. I think you could be a good fit.

This is an opportunity to push the boundaries of applied biology and artificial intelligence. You'll get exposed to a wide array of scientific problems and research methods, far beyond what one encounters working on a single drug program or within a traditional life sciences company.

About you

You have a deep desire to push the limits of what’s possible in therapeutic design, and a restless drive to solve real-world problems and iterate quickly. You are curious, high-agency and incredibly persistent.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\nABOUT THE ROLE\n\nWe are looking for exceptional antibody engineers and computational protein designers to help us evaluate, expand and apply the capabilities of our de novo antibody design models. You'll join an elite team of biologists, computational scientists and AI researchers.\n\nScientists at Chai are power users and test pilots of our AI platform. We probe the design space for novel targets and formats, validate in silico solutions for function in the lab, and distill empirical rules from the results. We execute experimental programs at scale that guide, train and evaluate next generation models, working closely with our AI research team. We partner with scientists from the world's leading pharma companies to push their discovery programs into new territory. I think you could be a good fit.\n\nThis is an opportunity to push the boundaries of applied biology and artificial intelligence. You'll get exposed to a wide array of scientific problems and research methods, far beyond what one encounters working on a single drug program or within a traditional life sciences company.\n\n\nABOUT YOU\n\nYou have a deep desire to push the limits of what’s possible in therapeutic design, and a restless drive to solve real-world problems and iterate quickly. You are curious, high-agency and incredibly persistent.\n\n - PhD or equivalent experience in the field—Antibody Engineering, Computational Biology, Protein Sciences.\n\n - Hands-on experience with design and characterization of antibody-based biologics. Proficient in molecular-biology workflows, binding and developability assays, inspecting structures in PyMOL or similar tools.\n\n - Track record of strong communication, collaboration and execution.\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"ab9b4d9d-03ff-4bf7-8d47-593443484f03","title":"Business Development","department":"Partnerships","team":"Partnerships","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2026-03-04T05:45:08.679+00:00","isListed":true,"isRemote":false,"workplaceType":"OnSite","address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/ab9b4d9d-03ff-4bf7-8d47-593443484f03","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/ab9b4d9d-03ff-4bf7-8d47-593443484f03/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

We are building out our partnerships founding team and looking to make a few key hires to anchor the effort. You will help set the terms and drive deal execution with the world's leading life sciences companies, establishing relationships that will shape our future.

These are complex transactions with sophisticated partners. You'll need to lean into the many details that make these partnerships work, while creating urgency and alignment around a common vision.

This is a critical role at a pivotal time for the business: Deal volume and demand are accelerating fast. It will be a lot of fun, a lot of work, and extraordinarily rewarding.

About you

We index on outlier performance and relentless execution. You sweat the small stuff, you think big, you always take ownership, and you strive for win-win outcomes. We can count on you.

We value biopharma domain experience and deal-making savvy, and we are also more than willing to make a bet on rising talent. Low-ego, high-EQ, motivated and mission-driven is what we're looking for.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\nABOUT THE ROLE\n\nWe are building out our partnerships founding team and looking to make a few key hires to anchor the effort. You will help set the terms and drive deal execution with the world's leading life sciences companies, establishing relationships that will shape our future.\n\nThese are complex transactions with sophisticated partners. You'll need to lean into the many details that make these partnerships work, while creating urgency and alignment around a common vision.\n\nThis is a critical role at a pivotal time for the business: Deal volume and demand are accelerating fast. It will be a lot of fun, a lot of work, and extraordinarily rewarding.\n\n\nABOUT YOU\n\nWe index on outlier performance and relentless execution. You sweat the small stuff, you think big, you always take ownership, and you strive for win-win outcomes. We can count on you.\n\nWe value biopharma domain experience and deal-making savvy, and we are also more than willing to make a bet on rising talent. Low-ego, high-EQ, motivated and mission-driven is what we're looking for.\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"16c7c2b9-1bb4-4bea-84be-2eadf913843f","title":"Software Engineer, Scientific Products","department":"Platform & Products","team":"Platform & Products","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2025-06-30T04:19:45.950+00:00","isListed":true,"isRemote":false,"workplaceType":"OnSite","address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/16c7c2b9-1bb4-4bea-84be-2eadf913843f","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/16c7c2b9-1bb4-4bea-84be-2eadf913843f/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

Build the computational workspace where scientists use Chai’s models and agents to design medicines. Molecular engineering still needs its own abstractions and product layer. You will help invent this category of software, owning the last mile from model capability to the experiments scientists run and what they learn.

About you

We look for engineers who can make sense of messy real-world problems and build simple solutions end to end. Former founders and engineers who have owned substantial products are a particularly good fit. Familiarity with the scientific domain is not required. We value technical depth, product judgment, and a record of building things that are meaningful and useful to people.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\n\n\nABOUT THE ROLE\n\nBuild the computational workspace where scientists use Chai’s models and agents to design medicines. Molecular engineering still needs its own abstractions and product layer. You will help invent this category of software, owning the last mile from model capability to the experiments scientists run and what they learn.\n\n - Work directly with scientists and Chai’s model researchers to understand their problems and decide what to build.\n\n - Own the work from the first customer conversation through to a product they depend on and appreciate, going as deep into the science, compute, models, research, and software as the problem requires.\n\n - Work forward deployed with our customers, ship across the stack, and refine the product and its core abstractions as you learn.\n\n\n\n\nABOUT YOU\n\nWe look for engineers who can make sense of messy real-world problems and build simple solutions end to end. Former founders and engineers who have owned substantial products are a particularly good fit. Familiarity with the scientific domain is not required. We value technical depth, product judgment, and a record of building things that are meaningful and useful to people.\n\n\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"bc51bebe-108a-4392-8b1d-91e460e6786c","title":"Design Engineer","department":"Platform & Products","team":"Platform & Products","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2025-06-30T14:49:37.958+00:00","isListed":true,"isRemote":false,"workplaceType":"OnSite","address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/bc51bebe-108a-4392-8b1d-91e460e6786c","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/bc51bebe-108a-4392-8b1d-91e460e6786c/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

Define and build the workspace that scientists use to develop new medicines. We believe tools like Cadence for electrical engineering and Photoshop for graphic design fundamentally changed how experts work by making complex work available on a computer. Molecular engineering deserves software of that caliber, and this category is yours to invent.

About you

We look for exceptional design taste, the engineering ability to prototype and ship, and a track record of distilling complex domains into simple products. You can get to the heart of a difficult problem without losing the details that matter.

Familiarity with the scientific domain is a bonus, but not a requirement. We care more about what you’ve built and the design decisions behind it.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\n\n\nABOUT THE ROLE\n\nDefine and build the workspace that scientists use to develop new medicines. We believe tools like Cadence for electrical engineering and Photoshop for graphic design fundamentally changed how experts work by making complex work available on a computer. Molecular engineering deserves software of that caliber, and this category is yours to invent.\n\n - Work directly with scientists and model researchers to understand how they experiment and make decisions, then turn that understanding into software for working with models and agents.\n\n - Invent the core concepts and interactions for molecular design on a computer.\n\n - Prototype and ship these interfaces and tools, owning the work from early design through production code.\n\n\n\n\nABOUT YOU\n\nWe look for exceptional design taste, the engineering ability to prototype and ship, and a track record of distilling complex domains into simple products. You can get to the heart of a difficult problem without losing the details that matter.\n\nFamiliarity with the scientific domain is a bonus, but not a requirement. We care more about what you’ve built and the design decisions behind it.\n\n\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"f9536a79-5e81-4d88-be04-8a654c5082d5","title":"Data Ops","department":"Research","team":"Research","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2026-06-08T20:33:42.802+00:00","isListed":true,"isRemote":false,"workplaceType":"OnSite","address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/f9536a79-5e81-4d88-be04-8a654c5082d5","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/f9536a79-5e81-4d88-be04-8a654c5082d5/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

We are looking for a data operations expert, or a fast-rising generalist, to help drive data generation initiatives here at Chai. Someone who operates with urgency, has strong communication and project management skills, and who has an analytical nature.

Data is vital to training frontier AI models, testing research hypotheses, and supporting our partners. You will set the vision and execute scaling of Chai’s lab-in-the-loop data platform, working hand-in-hand with our science and research teams. You don't need a biology background, but you will need to pick it up while learning about our AI methods.

This is a chance to push the boundaries of drug discovery and contribute to some of most advanced AI models ever imagined. Immerse yourself in technologies that represent the future of biotech, and position yourself at the forefront of this emerging field.

About you

Our ideal candidate can:

You have a deep desire to push the limits of what’s possible and restless drive to solve real-world problems by iterating fast. Exposure to startups or other intense environments is important.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\nABOUT THE ROLE\n\nWe are looking for a data operations expert, or a fast-rising generalist, to help drive data generation initiatives here at Chai. Someone who operates with urgency, has strong communication and project management skills, and who has an analytical nature.\n\nData is vital to training frontier AI models, testing research hypotheses, and supporting our partners. You will set the vision and execute scaling of Chai’s lab-in-the-loop data platform, working hand-in-hand with our science and research teams. You don't need a biology background, but you will need to pick it up while learning about our AI methods.\n\nThis is a chance to push the boundaries of drug discovery and contribute to some of most advanced AI models ever imagined. Immerse yourself in technologies that represent the future of biotech, and position yourself at the forefront of this emerging field.\n\n\nABOUT YOU\n\nOur ideal candidate can:\n\n - Design & drive complex projects and workflows, across multi-party relationships.\n\n - Translate research goals into concrete deliverables—experiments, deliverables, success criteria, SOWs, timelines, trackers, etc.\n\n - Communicate highly technical information with clarity.\n\n - Juggle concurrent projects and priorities, adapting quickly and keeping everyone in sync.\n\n - Develop a vision for how we scale our data program by orders of magnitude.\n\nYou have a deep desire to push the limits of what’s possible and restless drive to solve real-world problems by iterating fast. Exposure to startups or other intense environments is important.\n\n - Organized and scrappy\n\n - Detail-oriented and fast-moving\n\n - Flexible, proactive, ambitious\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"e60e0d79-622d-4251-b056-d380484d9dab","title":"Forward-Deployed Scientist","department":"Partnerships","team":"Partnerships","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2026-03-05T14:48:56.179+00:00","isListed":true,"isRemote":false,"workplaceType":"OnSite","address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/e60e0d79-622d-4251-b056-d380484d9dab","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/e60e0d79-622d-4251-b056-d380484d9dab/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

We are building out our science team and looking to make a few key hires to anchor the effort, operating at the frontiers of both drug discovery and AI research.

You will be an advisor to some of the most important drug programs of our time, helping solve disease at scale. You will become an expert in our partners' scientific and therapeutic problems. You will operate as a power user who knows all the ins and outs of our technology, ensuring that our partners deploy our platform to maximum effect.

You will be our eyes & ears on the ground, translating our partner's hardest asks into internal efforts, scoping and driving projects to tackle novel challenges alongside our research and engineering teams. Your findings will guide the future of our product, our models, and our approach.

It will be a lot of fun, a lot of work, and extraordinarily rewarding.

About you

We index on ravenous curiosity, outlier aptitude and collaboration smarts. You operate with urgency, have well-honed communication skills, and probably can't sleep if something isn't right.

We value academic research and drug discovery industry experience in antibody engineering, protein design, and computational methods. We are more than willing to bet on rising stars. Low-ego, high-EQ, and performance under pressure are what we're looking for.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\nABOUT THE ROLE\n\nWe are building out our science team and looking to make a few key hires to anchor the effort, operating at the frontiers of both drug discovery and AI research.\n\nYou will be an advisor to some of the most important drug programs of our time, helping solve disease at scale. You will become an expert in our partners' scientific and therapeutic problems. You will operate as a power user who knows all the ins and outs of our technology, ensuring that our partners deploy our platform to maximum effect.\n\nYou will be our eyes & ears on the ground, translating our partner's hardest asks into internal efforts, scoping and driving projects to tackle novel challenges alongside our research and engineering teams. Your findings will guide the future of our product, our models, and our approach. \n\nIt will be a lot of fun, a lot of work, and extraordinarily rewarding.\n\n\nABOUT YOU\n\nWe index on ravenous curiosity, outlier aptitude and collaboration smarts. You operate with urgency, have well-honed communication skills, and probably can't sleep if something isn't right.\n\nWe value academic research and drug discovery industry experience in antibody engineering, protein design, and computational methods. We are more than willing to bet on rising stars. Low-ego, high-EQ, and performance under pressure are what we're looking for.\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"49557cff-8121-4a6d-bfa3-83f2fabe080f","title":"Software Engineer, Compute Infrastructure","department":"Platform & Products","team":"Platform & Products","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2025-11-25T19:41:16.280+00:00","isListed":true,"isRemote":false,"workplaceType":"OnSite","address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/49557cff-8121-4a6d-bfa3-83f2fabe080f","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/49557cff-8121-4a6d-bfa3-83f2fabe080f/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

Build the compute infrastructure behind Chai’s next generation of models, scientific products, and autonomous research. Our research program and runtime inference constantly demand more compute, and the rate at which we bring it online and manage it effectively directly inflects Chai's velocity.

About you

We look for depth in distributed systems, compute infrastructure, and performance engineering, with demonstrated ownership of substantial production systems. You can reason across layers and make sound tradeoffs between complexity, reliability, and efficiency.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\n\n\nABOUT THE ROLE\n\nBuild the compute infrastructure behind Chai’s next generation of models, scientific products, and autonomous research. Our research program and runtime inference constantly demand more compute, and the rate at which we bring it online and manage it effectively directly inflects Chai's velocity.\n\n - Bring new clusters up and own the systems that make them useful across the business.\n\n - Work with researchers, engineers, and scientists to remove performance and reliability bottlenecks across the stack.\n\n - Optimize model inference and serving to run more scientific work with available compute.\n\n - Build the shared storage and security foundations that let people and agents use compute and data safely.\n\n\n\n\nABOUT YOU\n\nWe look for depth in distributed systems, compute infrastructure, and performance engineering, with demonstrated ownership of substantial production systems. You can reason across layers and make sound tradeoffs between complexity, reliability, and efficiency.\n\n\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"b5403125-6dc8-446b-990b-badcf584583d","title":"Engagement Management","department":"Partnerships","team":"Partnerships","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2026-03-04T17:20:12.015+00:00","isListed":true,"isRemote":false,"workplaceType":"OnSite","address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/b5403125-6dc8-446b-990b-badcf584583d","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/b5403125-6dc8-446b-990b-badcf584583d/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About this role

We are building out our founding partnerships team and looking to make a few key hires to anchor the effort.

Nothing is more important to our business than the success and growth of our partnerships, and that kind of responsibility is exactly what the right person will be eager to assume. You will do whatever it takes to ensure our partnerships are healthy and that Chai exceeds expectations.

You'll team up with phenomenal scientists to push forward multiple concurrent programs, accelerating time to clinic at an unprecedented rate. And you will emerge as a trusted thought partner, helping your counterparts fundamentally rethink their operating model in an era of AI.

You'll also be synthesizing what you learn into actionable intelligence for the rest of the company, helping us shape our product and our future. It will be a lot of fun, a lot of work, and extraordinarily rewarding.

About you

We index on outlier resourcefulness, integrity and execution. You sweat the small stuff, you value relationships, you hold timelines, and you keep everyone on the same page—without ever dropping balls. We can count on you, and so can our partners.

We value scientific and biopharma experience, and we are also more than willing to make a bet on exceptional people with translatable skills. Low-ego, high-EQ, motivated and mission-driven is what we're looking for.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\nABOUT THIS ROLE\n\nWe are building out our founding partnerships team and looking to make a few key hires to anchor the effort.\n\nNothing is more important to our business than the success and growth of our partnerships, and that kind of responsibility is exactly what the right person will be eager to assume. You will do whatever it takes to ensure our partnerships are healthy and that Chai exceeds expectations. \n\nYou'll team up with phenomenal scientists to push forward multiple concurrent programs, accelerating time to clinic at an unprecedented rate. And you will emerge as a trusted thought partner, helping your counterparts fundamentally rethink their operating model in an era of AI.\n\nYou'll also be synthesizing what you learn into actionable intelligence for the rest of the company, helping us shape our product and our future. It will be a lot of fun, a lot of work, and extraordinarily rewarding.\n\n\nABOUT YOU\n\nWe index on outlier resourcefulness, integrity and execution. You sweat the small stuff, you value relationships, you hold timelines, and you keep everyone on the same page—without ever dropping balls. We can count on you, and so can our partners.\n\nWe value scientific and biopharma experience, and we are also more than willing to make a bet on exceptional people with translatable skills. Low-ego, high-EQ, motivated and mission-driven is what we're looking for.\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"19fcda8f-b68a-465a-a960-edc49c7ecdb9","title":"Research Scientist","department":"Research","team":"Research","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2026-03-06T16:44:48.259+00:00","isListed":true,"isRemote":false,"workplaceType":"OnSite","address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/19fcda8f-b68a-465a-a960-edc49c7ecdb9","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/19fcda8f-b68a-465a-a960-edc49c7ecdb9/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

We are hiring research scientists with outlier insight who can drive new avenues for the work we pursue. From pre-training large diffusion models and architecture design, to post-training and inference time scaling, we draw upon the best ideas from within our domain and across the field.

Our models have moved beyond protein structure prediction into real-world therapeutic engineering—and we have only just begun. Our team hails from physics, math, theoretical computer science, computational biology and related disciplines. Everyone is capable and self-sufficient, and everyone helps foster a highly collaborative and collegial environment.

Our view is that executing on a long-term research program requires bringing together the right people, with access to the best resources, aligned towards common objectives. And nothing is more essential to our mission and our business than the progress of our research.

About you

We are looking for researchers driven by impact and foundational progress. We index on sustained focus, rigor and results—people who get obsessed with hard problems and don't give up easily. Folks with a nose for tackling the right questions at the right time, alongside an ample dose of grit and curiosity.

We value academic training, research track record, and proven industry accomplishments; we are also more than willing to make a bet on rising talent. We look for engineering capability as well as literature fluency.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\nABOUT THE ROLE\n\nWe are hiring research scientists with outlier insight who can drive new avenues for the work we pursue. From pre-training large diffusion models and architecture design, to post-training and inference time scaling, we draw upon the best ideas from within our domain and across the field.\n\nOur models have moved beyond protein structure prediction into real-world therapeutic engineering—and we have only just begun. Our team hails from physics, math, theoretical computer science, computational biology and related disciplines. Everyone is capable and self-sufficient, and everyone helps foster a highly collaborative and collegial environment.\n\nOur view is that executing on a long-term research program requires bringing together the right people, with access to the best resources, aligned towards common objectives. And nothing is more essential to our mission and our business than the progress of our research.\n\n\nABOUT YOU\n\nWe are looking for researchers driven by impact and foundational progress. We index on sustained focus, rigor and results—people who get obsessed with hard problems and don't give up easily. Folks with a nose for tackling the right questions at the right time, alongside an ample dose of grit and curiosity.\n\nWe value academic training, research track record, and proven industry accomplishments; we are also more than willing to make a bet on rising talent. We look for engineering capability as well as literature fluency.\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"ed0e6b18-1371-40c6-983b-c218ad5350c9","title":"Talent","department":"People & Ops","team":"People & Ops","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2026-01-15T17:26:23.749+00:00","isListed":true,"isRemote":false,"workplaceType":"OnSite","address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/ed0e6b18-1371-40c6-983b-c218ad5350c9","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/ed0e6b18-1371-40c6-983b-c218ad5350c9/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

Can you help us?

We are looking for a few exceptional individuals to anchor our founding talent team -- with an emphasis on research and engineering hiring in the near term. We index on curiosity, taste, resourcefulness, IQ and EQ in equal measure.

#1 Build an incredible company.

You will help design every detail of this org. You will refine your nose for outlier talent and exceptional genius, wherever it may be found. You will relentlessly tackle every aspect of every assignment you take on. You'll work with our founders and leaders day in and out.

#2 Learn everything, communicate expertly.

This job demands that you can hold an intelligent conversation with anyone at any level. You will ravenously learn everything about what we're doing, why we're doing it, and where we're headed -- so that you can tell our story with passion and authenticity. You care and build trust by keeping it real.

#3 Think + act different.

We don't think the status quo is good enough, and neither do you. You have consistently shown innate ability to think and act beyond what is expected in order to achieve out-of-distribution results. You turn insight into action, optimize for iteration over perfection, and operate with urgency & creativity in equal measure.

Where could this lead?

You will walk away from this position knowing that you were a force multiplier in accelerating humanity's progress towards better medicines and better understanding of biology. You will gain the know-how and the network to establish yourself as an industry operator, bolstering any plans you might have to found your own company one day.

It will be a lot of fun, a lot of work, and extraordinarily rewarding.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\nCAN YOU HELP US?\n\nWe are looking for a few exceptional individuals to anchor our founding talent team -- with an emphasis on research and engineering hiring in the near term. We index on curiosity, taste, resourcefulness, IQ and EQ in equal measure.\n\n#1 Build an incredible company.\n\nYou will help design every detail of this org. You will refine your nose for outlier talent and exceptional genius, wherever it may be found. You will relentlessly tackle every aspect of every assignment you take on. You'll work with our founders and leaders day in and out.\n\n#2 Learn everything, communicate expertly.\n\nThis job demands that you can hold an intelligent conversation with anyone at any level. You will ravenously learn everything about what we're doing, why we're doing it, and where we're headed -- so that you can tell our story with passion and authenticity. You care and build trust by keeping it real.\n\n#3 Think + act different.\n\nWe don't think the status quo is good enough, and neither do you. You have consistently shown innate ability to think and act beyond what is expected in order to achieve out-of-distribution results. You turn insight into action, optimize for iteration over perfection, and operate with urgency & creativity in equal measure.\n\n\nWHERE COULD THIS LEAD?\n\nYou will walk away from this position knowing that you were a force multiplier in accelerating humanity's progress towards better medicines and better understanding of biology. You will gain the know-how and the network to establish yourself as an industry operator, bolstering any plans you might have to found your own company one day.\n\nIt will be a lot of fun, a lot of work, and extraordinarily rewarding.\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"bc55b169-d23c-4e50-ac80-8dbe7ed64b72","title":"Internship","department":"Outliers & Polymaths","team":"Outliers & Polymaths","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2026-08-20T00:45:38.084+00:00","isListed":true,"isRemote":null,"workplaceType":null,"address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/bc55b169-d23c-4e50-ac80-8dbe7ed64b72","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/bc55b169-d23c-4e50-ac80-8dbe7ed64b72/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

Internship Opportunities

We do not offer internships—everything is too fast, too critical, too sensitive and too fun for it to be any other way :) However... we love to meet people who share our passion for shaping the future of medicine. So if that sounds like you, tell us more about yourself so that we can stay in touch.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\nINTERNSHIP OPPORTUNITIES\n\nWe do not offer internships—everything is too fast, too critical, too sensitive and too fun for it to be any other way :) However... we love to meet people who share our passion for shaping the future of medicine. So if that sounds like you, tell us more about yourself so that we can stay in touch.\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"9cc94a28-cac9-48a4-a44c-685a870b6288","title":"Scientist, Protein Design","department":"Science","team":"Science","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2026-08-29T03:29:01.854+00:00","isListed":true,"isRemote":null,"workplaceType":null,"address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/9cc94a28-cac9-48a4-a44c-685a870b6288","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/9cc94a28-cac9-48a4-a44c-685a870b6288/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

We are building out our science team and looking to make a few key hires to anchor the effort, operating at the frontiers of both drug discovery and AI research.

You will be an advisor to some of the most important drug programs of our time, helping solve disease at scale. You will become an expert in our partners' scientific and therapeutic problems. You will operate as a power user who knows all the ins and outs of our technology, ensuring that our partners deploy our platform to maximum effect.

You will be our eyes & ears on the ground, translating our partner's hardest asks into internal efforts, scoping and driving projects to tackle novel challenges alongside our research and engineering teams. Your findings will guide the future of our product, our models, and our approach.

It will be a lot of fun, a lot of work, and extraordinarily rewarding.

About you

We index on ravenous curiosity, outlier aptitude and collaboration smarts. You operate with urgency, have well-honed communication skills, and probably can't sleep if something isn't right.

We value academic research and drug discovery industry experience in antibody engineering, protein design, and computational methods. We are more than willing to bet on rising stars. Low-ego, high-EQ, and performance under pressure are what we're looking for.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\nABOUT THE ROLE\n\nWe are building out our science team and looking to make a few key hires to anchor the effort, operating at the frontiers of both drug discovery and AI research.\n\nYou will be an advisor to some of the most important drug programs of our time, helping solve disease at scale. You will become an expert in our partners' scientific and therapeutic problems. You will operate as a power user who knows all the ins and outs of our technology, ensuring that our partners deploy our platform to maximum effect.\n\nYou will be our eyes & ears on the ground, translating our partner's hardest asks into internal efforts, scoping and driving projects to tackle novel challenges alongside our research and engineering teams. Your findings will guide the future of our product, our models, and our approach. \n\nIt will be a lot of fun, a lot of work, and extraordinarily rewarding.\n\n\nABOUT YOU\n\nWe index on ravenous curiosity, outlier aptitude and collaboration smarts. You operate with urgency, have well-honed communication skills, and probably can't sleep if something isn't right.\n\nWe value academic research and drug discovery industry experience in antibody engineering, protein design, and computational methods. We are more than willing to bet on rising stars. Low-ego, high-EQ, and performance under pressure are what we're looking for.\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"47c72f5e-62bc-472f-9173-40fc67c0c71a","title":"First Finance Hire","department":"Strategy","team":"Strategy","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2026-08-31T17:25:21.719+00:00","isListed":true,"isRemote":null,"workplaceType":null,"address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/47c72f5e-62bc-472f-9173-40fc67c0c71a","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/47c72f5e-62bc-472f-9173-40fc67c0c71a/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

We are making our first finance hire. Someone we can trust to own Chai's financial operating system end to end. Chai is a small, fast-growing company with complex financial operations; heavy spend on compute and data acquisition; and pharmaceutical partnerships with complex revenue recognition and compliance requirements. We need someone who can make sure the machinery underneath the business is exceptionally well run, and give us the visibility to make good decisions as we scale.

You will own the quality of our books and close process, build a trusted view of where our money is going, and take over the financial model and cash forecast. You'll manage accounting and finance vendors, improve all systems and controls, and lead our audit readiness.

Once the foundations are in place, we expect your attention will turn towards strategic questions: allocating capital, modeling major investments, negotiating important relationships, and generally supporting key decisions as we grow.

About you

You are a financial generalist who combines operational rigor with strong financial judgment. You are sophisticated enough to understand the entire financial picture of the company, but hands-on enough to personally chase down a strange invoice, manage an accounting firm, negotiate a vendor renewal, or rebuild a cash forecast. Nothing is beneath you if it matters to the business.

You likely have meaningful experience inside a startup. You may have been an early finance hire or second-in-command at a high-growth technology company, come from strategic finance after rigorous training in banking, or started in accounting and grown into a broader role.

Most importantly, you own outcomes. When something important falls between functions, your instinct is to understand it, fix it, and build a system so it stays fixed. All with a mindset of making complexity disappear and avoiding unnecessary process.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\nABOUT THE ROLE\n\nWe are making our first finance hire. Someone we can trust to own Chai's financial operating system end to end. Chai is a small, fast-growing company with complex financial operations; heavy spend on compute and data acquisition; and pharmaceutical partnerships with complex revenue recognition and compliance requirements. We need someone who can make sure the machinery underneath the business is exceptionally well run, and give us the visibility to make good decisions as we scale.\n\nYou will own the quality of our books and close process, build a trusted view of where our money is going, and take over the financial model and cash forecast. You'll manage accounting and finance vendors, improve all systems and controls, and lead our audit readiness.\n\nOnce the foundations are in place, we expect your attention will turn towards strategic questions: allocating capital, modeling major investments, negotiating important relationships, and generally supporting key decisions as we grow.\n\n\nABOUT YOU\n\nYou are a financial generalist who combines operational rigor with strong financial judgment. You are sophisticated enough to understand the entire financial picture of the company, but hands-on enough to personally chase down a strange invoice, manage an accounting firm, negotiate a vendor renewal, or rebuild a cash forecast. Nothing is beneath you if it matters to the business.\n\nYou likely have meaningful experience inside a startup. You may have been an early finance hire or second-in-command at a high-growth technology company, come from strategic finance after rigorous training in banking, or started in accounting and grown into a broader role.\n\nMost importantly, you own outcomes. When something important falls between functions, your instinct is to understand it, fix it, and build a system so it stays fixed. All with a mindset of making complexity disappear and avoiding unnecessary process.\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"9be875bd-46f0-4653-9851-88e2ce49eb64","title":"Software Engineer, Developer & Research Platform","department":"Platform & Products","team":"Platform & Products","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2026-10-12T22:19:50.602+00:00","isListed":true,"isRemote":null,"workplaceType":null,"address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/9be875bd-46f0-4653-9851-88e2ce49eb64","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/9be875bd-46f0-4653-9851-88e2ce49eb64/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

Build the platform that shortens the time it takes researchers and engineers to test ideas, ship software, and learn from experiments. We believe the software factory is just as important as the software itself, and you will build that factory for people and agents, including:

About you

We look for strong systems engineering, developer taste, and a record of making other technical people more effective. You understand how researchers and engineers work, can go deep into the systems they depend on, and build tools they want to use.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\n\n\nABOUT THE ROLE\n\nBuild the platform that shortens the time it takes researchers and engineers to test ideas, ship software, and learn from experiments. We believe the software factory is just as important as the software itself, and you will build that factory for people and agents, including:\n\n - Shipping the research platform where people and agents launch experiments, compare results, and decide what to try next.\n\n - Designing systems that let coding agents take on more development, testing, and code review.\n\n - Setting up better development environments, faster tests, and reliable deploys.\n\n\n\n\nABOUT YOU\n\nWe look for strong systems engineering, developer taste, and a record of making other technical people more effective. You understand how researchers and engineers work, can go deep into the systems they depend on, and build tools they want to use.\n\n\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"ad8dd3de-8139-4385-8c5a-566a359e9be0","title":"Software Engineer, AI Platform","department":"Platform & Products","team":"Platform & Products","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2026-10-12T22:21:17.000+00:00","isListed":true,"isRemote":null,"workplaceType":null,"address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/ad8dd3de-8139-4385-8c5a-566a359e9be0","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/ad8dd3de-8139-4385-8c5a-566a359e9be0/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

Build the AI platform that lets scientists direct research programs with agents. We believe that as Chai's models get more powerful, scientists will focus more on fundamental problems and biological hypotheses, and delegate more of the subtasks to answer them to agents. Making this possible requires inventing the abstractions through which people, agents, and Chai’s models collaborate.

About you

We look for technical depth, strong software architecture, and product judgment, with experience building complex applications or agent systems. You can find clear abstractions in a messy domain and build systems that hold up as their scope grows. We value a practical understanding of where agents fail and how to tell whether they’re doing useful work.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\n\n\nABOUT THE ROLE\n\nBuild the AI platform that lets scientists direct research programs with agents. We believe that as Chai's models get more powerful, scientists will focus more on fundamental problems and biological hypotheses, and delegate more of the subtasks to answer them to agents. Making this possible requires inventing the abstractions through which people, agents, and Chai’s models collaborate.\n\n - Work with scientists and model researchers to define how agents use Chai’s foundation models to design molecules and guide experiments.\n\n - Build products that shorten the cycle from idea ➝ to experiment ➝ to the next decision, while scientists monitor and direct the work.\n\n - Build the core abstractions for agent execution, model inference, and scientific tools so new capabilities come together fluidly across the workspace.\n\n\n\n\nABOUT YOU\n\nWe look for technical depth, strong software architecture, and product judgment, with experience building complex applications or agent systems. You can find clear abstractions in a messy domain and build systems that hold up as their scope grows. We value a practical understanding of where agents fail and how to tell whether they’re doing useful work.\n\n\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"64fcb54e-d008-4551-858a-5c0f3b48f270","title":"Research Engineer","department":"Research","team":"Research","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2024-09-05T02:38:07.582+00:00","isListed":true,"isRemote":false,"workplaceType":"OnSite","address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/64fcb54e-d008-4551-858a-5c0f3b48f270","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/64fcb54e-d008-4551-858a-5c0f3b48f270/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

Make our models performant, fast, and reliable at scale by developing the core frameworks used to train and evaluate our ML models.

Chai's models are moving beyond protein structure prediction into real-world therapeutic engineering. This is a chance to push the frontier of AI drug design, working alongside a rigorous and craft-obsessed team.

About you

Ideal backgrounds include deep industry experience working with top AI/ML teams on the kinds of problems we describe above—with strong software system design skills, proficiency in Python, and Pytorch or JAX fluency. We look for technical spikes where you have gone deep and demonstrated exceptional impact on real-world problems and systems.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\nABOUT THE ROLE\n\nMake our models performant, fast, and reliable at scale by developing the core frameworks used to train and evaluate our ML models.\n\n - Build datasets and algorithms to systematically evaluate and monitor model performance.\n\n - Analyze model failure modes, working closely with researchers on experiments to mitigate them.\n\n - Own the distributed training stack, removing runtime and reliability bottlenecks across all layers of the stack and architecture—parallelism, quantization, and kernel optimization and whatever else might move the needle.\n\n - Own and contribute to our auto research and auto kernels frameworks.\n\nChai's models are moving beyond protein structure prediction into real-world therapeutic engineering. This is a chance to push the frontier of AI drug design, working alongside a rigorous and craft-obsessed team.\n\n\nABOUT YOU\n\nIdeal backgrounds include deep industry experience working with top AI/ML teams on the kinds of problems we describe above—with strong software system design skills, proficiency in Python, and Pytorch or JAX fluency. We look for technical spikes where you have gone deep and demonstrated exceptional impact on real-world problems and systems.\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"dd8bf1b0-be34-42ba-94f7-76e6ebe204f6","title":"Research Engineer, ML Infrastructure","department":"Research","team":"Research","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2026-09-24T23:45:49.396+00:00","isListed":true,"isRemote":null,"workplaceType":null,"address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/dd8bf1b0-be34-42ba-94f7-76e6ebe204f6","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/dd8bf1b0-be34-42ba-94f7-76e6ebe204f6/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

Make our models performant, resource efficient and reliable at scale by developing the core frameworks for model training and evaluation, in close partnerships with fellow researchers and engineers.

Chai's models are moving beyond protein structure prediction into real-world therapeutic engineering. This is a chance to push the frontier of AI drug design, working alongside a rigorous and craft-obsessed team.

About you

Ideal backgrounds include deep industry experience working with top AI/ML teams on the kinds of problems and systems we describe above—with strong software system design skills, proficiency in Python, and Pytorch or JAX fluency. We look for technical spikes where you have gone deep and demonstrated exceptional impact on real-world problems and systems.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\nABOUT THE ROLE\n\nMake our models performant, resource efficient and reliable at scale by developing the core frameworks for model training and evaluation, in close partnerships with fellow researchers and engineers.\n\n - Build our training stack across model, layer, and kernel levels; optimize workloads through parallelism, quantization, and custom kernels.\n\n - Profile end-to-end training runs on large GPU clusters; eliminate bottlenecks and failures; monitor throughput, utilization, and uptime.\n\n - Ensure new model architectures and training recipes scale efficiently, from early experiments to frontier-scale runs.\n\n - Make our ML training stack maximally reliable: fault tolerance, checkpointing, and deterministic orchestration for long-running, large-scale jobs.\n\nChai's models are moving beyond protein structure prediction into real-world therapeutic engineering. This is a chance to push the frontier of AI drug design, working alongside a rigorous and craft-obsessed team.\n\n\nABOUT YOU\n\nIdeal backgrounds include deep industry experience working with top AI/ML teams on the kinds of problems and systems we describe above—with strong software system design skills, proficiency in Python, and Pytorch or JAX fluency. We look for technical spikes where you have gone deep and demonstrated exceptional impact on real-world problems and systems.\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"4150df11-eb0a-4449-bee8-db7f0ed0da98","title":"Brand and Marketing","department":"Strategy","team":"Strategy","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2026-09-30T06:40:10.961+00:00","isListed":true,"isRemote":null,"workplaceType":null,"address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/4150df11-eb0a-4449-bee8-db7f0ed0da98","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/4150df11-eb0a-4449-bee8-db7f0ed0da98/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

We are making our first marketing hire, someone to own Chai’s brand and the story we tell, with a clear thesis for what matters and how to stand out. Our audiences ranging from pharma executives and scientists to AI researchers and engineers. You’ll decide where our story shows up, online and off: which platforms, events, dinners, talks, and launches are worth doing, and which aren’t. When we show up, you make sure it’s unmistakably Chai.

This isn’t demand gen. It’s taste, judgment, and editorial instinct, applied exceptionally well. Early priorities include:

About you

You are a brand builder with taste and operational discipline. You can set a creative direction and hold an agency to it, and are also hands-on enough to rewrite a headline yourself, fix a slide, chase an event vendor, or sweat the details of a dinner. You say no more often than yes, choosing the few things worth doing exceptionally well.

You have been close to building at least one respected technology brand. You may have been a founding marketing team member at a high-growth startup, led brand or creative at a design-forward company, or run experiences at a firm known for them. Biotech or pharma experience isn't required; genuine curiosity and the ability to learn quickly are.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\nABOUT THE ROLE\n\nWe are making our first marketing hire, someone to own Chai’s brand and the story we tell, with a clear thesis for what matters and how to stand out. Our audiences ranging from pharma executives and scientists to AI researchers and engineers. You’ll decide where our story shows up, online and off: which platforms, events, dinners, talks, and launches are worth doing, and which aren’t. When we show up, you make sure it’s unmistakably Chai.\n\nThis isn’t demand gen. It’s taste, judgment, and editorial instinct, applied exceptionally well. Early priorities include:\n\n - making key moments count at JPM, partner events, and the AI and science conferences where we need to stand out;\n\n - helping our founders and team turn their work into posts, talks, and essays that reach the right people;\n\n - making Chai more legible and compelling to the people we want to hire, including those with no background in biology;\n\n - putting a playbook in place so we can move faster, with rigor.\n\n\nABOUT YOU\n\nYou are a brand builder with taste and operational discipline. You can set a creative direction and hold an agency to it, and are also hands-on enough to rewrite a headline yourself, fix a slide, chase an event vendor, or sweat the details of a dinner. You say no more often than yes, choosing the few things worth doing exceptionally well.\n\nYou have been close to building at least one respected technology brand. You may have been a founding marketing team member at a high-growth startup, led brand or creative at a design-forward company, or run experiences at a firm known for them. Biotech or pharma experience isn't required; genuine curiosity and the ability to learn quickly are.\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."},{"id":"8c45d5b1-d0fa-4611-9cff-1ed5e6f9cba4","title":"Strategy","department":"Strategy","team":"Strategy","employmentType":"FullTime","location":"San Francisco office","secondaryLocations":[],"publishedAt":"2026-09-30T16:38:42.386+00:00","isListed":true,"isRemote":null,"workplaceType":null,"address":{"postalAddress":{"addressRegion":"California","addressCountry":"United States","addressLocality":"San Francisco"}},"jobUrl":"https://jobs.ashbyhq.com/chaidiscovery/8c45d5b1-d0fa-4611-9cff-1ed5e6f9cba4","applyUrl":"https://jobs.ashbyhq.com/chaidiscovery/8c45d5b1-d0fa-4611-9cff-1ed5e6f9cba4/application","descriptionHtml":"

About Chai Discovery

Chai Discovery builds the computer-aided design suite for molecules. Eli Lilly, GSK, Pfizer, Bristol Myers Squibb, argenx and Novartis all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.

We train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.

We value diverse perspectives and are ready to find greatness in unexpected places.

About the role

We are building a strategy team to take on the hardest open questions about our business and turn them into decisions we act on.

Chai's business model has no real precedent. We sell a new kind of technology into a very large market, in an era where few people can say with confidence where things are headed. The questions are hard and the answers consequential: how we price, which segments and products we expand into, and what makes our position durable. You'll need to be ready to embed with teams on problems ranging from scaling lab capacity and buy versus build compute to winning the war for talent.

The work runs from framing to implementation. You'll scope a problem, run primary research with customers and outside experts, build the quantitative case, reach a conclusion, and see it through. A project isn't done when the memo is written. It's done when the decision is made and in place.

About you

You are a structured, quantitative thinker with good instincts. You produce conclusions, not just inputs. You know how to influence, pushing decisions across teams until they land.

You are comfortable making justified assumptions with incomplete information, and disciplined about revisiting them. You know which threads to pull on an expert call. You have a nose for connecting dots, extracting signal, and folding new data points into the larger picture.

You likely trained in management consulting, venture or growth investing, or quantitative research, and may have moved into strategy or special projects at a high-growth technology company. Data science or CS experience is a plus. Biotech or pharma experience isn't required—range across industries and situations is valuable, as is the ability to learn a technical domain quickly.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly.

","descriptionPlain":"ABOUT CHAI DISCOVERY\n\nChai Discovery builds the computer-aided design suite for molecules. Eli Lilly https://endpoints.news/eli-lilly-chai-discovery-sign-ai-software-deal/, GSK https://endpoints.news/chai-discovery-signs-gsk-deal-to-make-biologics-with-ai/, Pfizer https://www.forbes.com/sites/amyfeldman/2026/06/04/why-pfizer-and-eli-lilly-are-betting-on-this-13-billion-ai-drug-discovery-startup/, Bristol Myers Squibb https://www.linkedin.com/feed/update/urn:li:activity:7496300911523246080/, argenx https://x.com/chaidiscovery/status/2077422480617267230?s=20 and Novartis https://www.chaidiscovery.com/news/novartis-partnership all use Chai to power drug discovery programs. AI is reinventing life sciences the same way it reinvented software engineering, and our team is building that future.\n\nWe train frontier models that learn the underlying foundations of biochemical structure and interaction. We pair this with a computational workspace to iterate on molecules from idea to medicine, helping scientists move faster and develop medicines beyond the reach of existing methods.\n\nWe value diverse perspectives and are ready to find greatness in unexpected places.\n\n\nABOUT THE ROLE\n\nWe are building a strategy team to take on the hardest open questions about our business and turn them into decisions we act on.\n\nChai's business model has no real precedent. We sell a new kind of technology into a very large market, in an era where few people can say with confidence where things are headed. The questions are hard and the answers consequential: how we price, which segments and products we expand into, and what makes our position durable. You'll need to be ready to embed with teams on problems ranging from scaling lab capacity and buy versus build compute to winning the war for talent.\n\nThe work runs from framing to implementation. You'll scope a problem, run primary research with customers and outside experts, build the quantitative case, reach a conclusion, and see it through. A project isn't done when the memo is written. It's done when the decision is made and in place.\n\n\nABOUT YOU\n\nYou are a structured, quantitative thinker with good instincts. You produce conclusions, not just inputs. You know how to influence, pushing decisions across teams until they land.\n\nYou are comfortable making justified assumptions with incomplete information, and disciplined about revisiting them. You know which threads to pull on an expert call. You have a nose for connecting dots, extracting signal, and folding new data points into the larger picture.\n\nYou likely trained in management consulting, venture or growth investing, or quantitative research, and may have moved into strategy or special projects at a high-growth technology company. Data science or CS experience is a plus. Biotech or pharma experience isn't required—range across industries and situations is valuable, as is the ability to learn a technical domain quickly.\n\n\nWE OFFER\n\nThe opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect and promote a culture of high velocity and ownership. We compensate our team accordingly."}],"apiVersion":"1"}